Institut de Biologie de l'École Normale Supérieure ENS . CNRS UMR8197 . Inserm U1024 Directeur : Pierre Paoletti

Cécile Charrier awardee of the ERC "Starting Grants" 2018 call.

This contract funds young researchers of all nationalities, to enable them to carry out innovative and very high level research projects.

Régis Ferrière receives NSF "Dimensions of Diversity" 2018 award

A global ocean atlas of eukaryotic genes

Quentin Carradec, Eric Pelletier [...] Fabio Rocha, Leila Tirichine [...] Amos Kirilovsky, [...] Raphaël Méheust[...] Céline Dimier [...] Tara Oceans Coordinators [...] Eric Karsenti [...] Chris Bowler, Patrick Wincker.

doi: 10.1038/s41467-017-02342-1. Nature Communications, 25 janvier 2018.

A Penalized Likelihood Framework For High-Dimensional Phylogenetic Comparative Methods And An Application To New-World Monkeys Brain Evolution.

Julien Clavel, Leandro Aristide, Hélène Morlon.

Syst Biol. 2018 Jun 19. doi: 10.1093/sysbio/syy045.

Active intermixing of indirect and direct neurons builds the striatal mosaic

Tinterri A, Menardy F, Diana MA, Lokmane L, Keita M, Coulpier F, Lemoine S, Mailhes C, Mathieu B, Merchan-Sala P, Campbell K, Gyory I, Grosschedl R, Popa D, Garel S

Nat Commun. 2018 Nov 9;9(1):4725. doi: 10.1038/s41467-018-07171-4.

An inter‐dimer allosteric switch controls NMDA receptor activity.

Jean‐Baptiste Esmenjaud, David Stroebel, Kelvin Chan, Teddy Grand, Mélissa David, Lonnie Wollmuth, Antoine Taly, Pierre Paoletti.

EMBO Journal (2018) e99894, DOI 10.15252/embj.201899894

Asymmetric adhesion of rod-shaped bacteria controls microcolony morphogenesis

Marie-Cécilia Duvernoy, Thierry Mora, Maxime Ardré, Vincent Croquette, David Bensimon, Catherine Quilliet, Jean-Marc Ghigo, Martial Balland, Christophe Beloin, Sigolène Lecuyer, Nicolas Desprat.

Nature Communications, volume 9, Article number: 1120 (2018). doi:10.1038/s41467-018-03446-y

Cellular origin, tumour progression and pathogenic mechanisms of cutaneous neurofibromas revealed by mice with Nf1 knockout in boundary cap cells

Radomska KJ, Coulpier F, Gresset A, Schmitt A, Debbiche A, Lemoine S, Wolkenstein P, Vallat JM, Charnay P, Topilko P.

Cancer Discov. 2018 Oct 22. pii: CD-18-0156. doi: 10.1158/2159-8290.CD-18-0156.

Chromosome evolution at the origin of the ancestral vertebrate genome

Christine Sacerdot, Alexandra Louis, Céline Bon, Camille Berthelot and Hugues Roest Crollius.

Genome Biol. 2018 Oct 17;19(1): 166. doi: 10.1186/s13059-018-1559-1.

Clade diversification dynamics and the biotic and abiotic controls of speciation and extinction rates.

Robin Aguilée, Fanny Gascuel, Amaury Lambert, Régis Ferrière.

Nat Commun. 2018 Aug 1;9(1):3013. doi: 10.1038/s41467-018-05419-7.

Contrasting impacts of competition on ecological and social trait evolution in songbirds

Jonathan P. Drury, Joseph A. Tobias, Kevin J. Burns, Nicholas A. Mason, Allison J. Shultz, Hélène Morlon.

PLoS Biology. doi.org/10.1371/journal.pbio.2003563. January 31, 2018

DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis

Amr Nassrallah, Martin Rougée, Clara Bourbousse, [...] Chris Bowler, Vicente Rubio, Fredy Barneche.

eLife 2018;7: e37892 doi: 10.7554/eLife.37892

Developmental and cancer-associated plasticity of DNA replication preferentially targets GC-poor, lowly expressed and late-replicating regions

X.Wu, H.Kabalane, M.Kahli, [...] A.Arneodo, B.Audit, O.Hyrien

Nucleic Acids Res. 2018 Sep 5. doi:10.1093/nar/gky797

Dissection of DNA double-strand break repair using novel single-molecule forceps

Jing L. Wang, Camille Duboc, Qian Wu, Takashi Ochi, Shikang Liang, Susan E. Tsutakawa, Susan P. Lees-Miller, Marc Nadal, John A. Tainer, Tom L. Blundell, Terence R. Strick

Nat Struct Mol Biol. 2018 May 21. doi: 10.1038/s41594-018-0065-1

Endocytosis-mediated siderophore uptake as a strategy for Fe acquisition in diatoms

Elena Kazamia, Robert Sutak, Javier Paz-Yepes, Richard G. Dorrell, Fabio Rocha Jimenez Vieira, Jan Mach, Joe Morrissey, Sébastien Leon, France Lam, Eric Pelletier, Jean-Michel Camadro, Chris Bowler, Emmanuel Lesuisse

Sci Adv. 2018 May 16;4(5):eaar4536. doi: 10.1126/sciadv.aar4536. eCollection 2018 May.

Ependymal cilia beating induces an actin network to protect centrioles against shear stress.

Alexia Mahuzier, Asm Shihavuddin, Clémence Fournier, Pauline Lansade, Marion Faucourt, Nikita Menezes, Alice Meunier, Meriem Garfa-Traoré, Marie-France Carlier, Raphael Voituriez, Auguste Genovesio, Nathalie Spassky & Nathalie Delgehyr.

Nat Commun. 2018 Jun 11;9(1):2279. doi: 10.1038/s41467-018-04676-w.

Jean-François Brunet, lauréat du prix de la FRM: "Brixham Foundation 2018"

Ce Prix est issu d’un don de cette fondation pour la recherche sur le cerveau.

Mib1 prevents Notch Cis-inhibition to defer differentiation and preserve neuroepithelial integrity during neural delamination.

Baek C, Freem L, Goïame R, Sang H, Morin X, Tozer S.

PLoS Biol. 2018 Apr 30;16(4):e2004162. doi: 10.1371/journal.pbio.2004162.

Microglia and early brain development: An intimate journey.

Morgane S. Thion, Florent Ginhoux, Sonia Garel.

Thion et al., Science 362, 185–189 (2018) 12 October 2018

Monitored eCLIP: high accuracy mapping of RNA-protein interactions.

Rémi Hocq, Janio Paternina, Quentin Alasseur, Auguste Genovesio, Hervé Le Hir.

Nucleic Acids Research, 2018 Sep 25. doi: 10.1093/nar/gky858.

Morgane Thion, lauréate du prix "Les Grandes Avancées Françaises en Biologie" de l’Académie des Sciences en 2018.

Natural Genetic Variation in a Multigenerational Phenotype in C. elegans

Lise Frezal, Emilie Demoinet, Christian Braendle, Eric Miska, Marie-Anne Felix.

Curr Biol. 2018 Aug 20;28(16):2588-2596.e8. doi: 10.1016/j.cub.2018.05.091.

RSAT 2018: regulatory sequence analysis tools 20th anniversary

Nga Thi Thuy Nguyen, Bruno Contreras-Moreira, Jaime A Castro-Mondragon, Walter Santana-Garcia, Raul Ossio, Carla Daniela Robles-Espinoza, Mathieu Bahin, Samuel Collombet, Pierre Vincens, Denis Thieffry, Jacques van Helden, Alejandra Medina-Rivera, Morgane Thomas-Chollier

Nucleic Acids Res. 2018 May 2. doi: 10.1093/nar/gky317

Single-cell genomics of multiple uncultured stramenopiles reveals underestimated functional diversity across oceans

Yoann Seeleuthner, Samuel Mondy [...] Céline Dimier [...] Tara Oceans Coordinators [...] Chris Bowler [...] Eric Karsenti [...] Colomban de Vargas, Patrick Wincker.

doi:10.1038/s41467-017-02235-3, Nature Communications, 22 janvier 2018.

The epibiotic life of the cosmopolitan diatom Fragilariopsis doliolus on heterotrophic ciliates in the open ocean

Flora J. Vincent, Sébastien Colin, Sarah Romac, Eleonora Scalco, Lucie Bittner, Yonara Garcia, Rubens M. Lopes, John R. Dolan, Adriana Zingone, Colomban de Vargas & Chris Bowler.

The ISME Journal (2018). doi:10.1038/s41396-017-0029-1