logo-ebgm Equipe de Bioinformatique Génomique et Moléculaire

Ecole Normale Supérieure - INSERM - U436


The knowledge of the location of duplicated regions into complete genomes is a major source of information to understand the mechanisms of their evolution. The primary objective of SIMCOGEN (SIMilar regions into the COmplete GENomes) is to build a repository registering all pairs of similar regions found into a lot of complete genomes. Two regions are similar if the identity of their nucleotidic sequences is greater than Smin for a length greater than Lmin.

Data are registered in the database using a relational model. The main tables include the location of the similar pairs and the informations describing the known regions of analysed chromosomes. Using the ASSIRC/D-ASSIRC software, the search of similar regions has been performed for a lot of chromosomes whose complete sequence is available. Are included procaryotic (B. subtilis, E. coli, M. genitalium,...) and eucaryotic organisms (S. cerevisiae,...).

Related publications


SIMCOGEN could be interactively consulted at http://www.simcogen.ens.fr.

Flat files registering data included into SIMCOGEN are freely available at the following address: ftp://ftp.biologie.ens.fr/pub/simcogen


Materials on this site are copyrighted and maintained by P. Vincens <vincens@biologie.ens.fr>.
Last modified: Wed Apr 3 19:06:00 MEST 2002