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GENOME-WIDE STUDIES ON THE NUCLEAR PDR3-CONTROLLED RESPONSE TO MITOCHONDRIAL
DYSFUNCTION IN YEAST
Frédéric DEVAUX, Elvira CARVAJAL, Scott MOYE-ROWLEY and Claude JACQ FEBS letters, 2002 |
|
GENOME-WIDE STUDIES ON THE NUCLEAR PDR3-CONTROLLED RESPONSE TO MITOCHONDRIAL
DYSFUNCTION IN YEAST
Frédéric DEVAUX, Elvira CARVAJAL, Scott MOYE-ROWLEY and Claude JACQ FEBS letters, 2002 |
Numerical values used to create figure1:
genes activated by Pdr3p* in rho0 cells
* PDR3p activated by the mitochondrial dysfunction
| Experiment | rho0
vs Rho+ |
rho0
vs Delta pdr3 rho0 |
rho0
vs Rho+ |
rho0
vs D pdr3rho0 |
| Strain | SEY | SEY | FY | FY |
| PDR5 | 7.3 | 5.7 | 8.3 | 11.4 |
| PDR15 | 7.7 | 6.3 | 10.5 | 10.8 |
| YOR049c | 5.9 | 4.2 | 9.3 | 4.4 |
| YAL061w | 3.5 | 2.5 | 17.3 | 6.7 |
| YKL071w | 3.9 | 2.4 | 5 | 3 |
| YGR035c | 2.6 | 2 | 4.4 | 2.9 |
| ICT1 | 2.3 | 1.9 | 2.6 | 2.3 |
| YLR346c | 1.8 | 2.3 | 4.2 | 3.4 |
| yor152c | 2.4 | 3.3 | 2 | 1.9 |
| PDR10 | ND | ND | 2.9 | 2.8 |
| SNQ2 | 1.9 | 1.8 | 1.9 | 1.8 |
| PDR3 | 4 | ND | 5 | ND |
| YGP1 | 3 | 1.9 | 8.9 | 1.3 |
| SCS7 | 1.7 | 1.4 | 2.2 | 4.2 |
| CTT1 | 2 | 1.1 | 2.7 | 2.5 |
| CYB2 | 2.1 | 1 | 2.5 | 1.9 |
| ACO1 | 3.9 | 0.9 | 2.7 | 1.9 |
| IDH2 | 3.5 | 0.8 | 4 | 1.1 |
| IDH1 | 3.3 | 0.8 | 4.3 | 1.3 |
| YOR135c | 2.8 | 0.8 | 3.9 | 1.6 |
| PDH1 | 2.3 | 0.8 | 3.9 | 1.6 |
| GDB1 | 2.1 | 1.5 | 3.4 | 1.4 |
| GLC3 | 2.1 | 0.9 | ND | 1.5 |
| YCL042w | 2 | 1.2 | 4.2 | 1.1 |
| YOR173w | 1.8 | 1.2 | 5 | 1.1 |
| GPH1 | 1.8 | 1 | 6.5 | 1.4 |
| GLK1 | 1.8 | 1 | 5.1 | 1.6 |
| PGM2 | 1.8 | 1.1 | 4.5 | 1.4 |
| GAC1 | 1.8 | 1.2 | 3.8 | ND |
| YTP1 | 2.5 | 0.9 | 2.4 | 1.3 |
| YLR149c | 1.8 | 0.8 | 3.5 | 1.8 |
| ECM4 | 2.1 | 1.1 | 2.8 | 0.8 |
| YGL157w | 2.1 | 1.5 | 2.6 | 1.7 |
| DLD1 | 2.4 | 1.1 | 2.2 | 1.6 |
| YMR291w | 1.8 | 1.2 | 2.9 | 1.6 |
| GRE2 | 2 | 1.3 | 2.7 | 1.6 |
| BAG7 | 1.9 | 0.8 | 3 | 1.2 |
| NAM2 | 2.1 | 0.6 | 1.8 | 1.1 |
| CCC2 | 2.1 | 0.8 | 1.8 | 0.8 |
| YNR040w | 2.2 | 0.8 | 1.8 | 0.9 |
| YDR116c | 2.1 | 0.7 | 1.9 | ND |
| CAF17 | 2.1 | 0.9 | 1.8 | 0.9 |
| YMR145c | 2.1 | 0.8 | 1.9 | 1.3 |
| YGL039w | 2 | 1.3 | 2.3 | 1.5 |
| YMR102c | 1.8 | 1.4 | 1.8 | 1.3 |
| MRP1 | 1.9 | 0.7 | 1.8 | 0.9 |
| YER053c | 2 | 0.7 | 2.5 | 1.3 |
| MSF1 | 1.9 | 0.7 | 1.8 | 1.5 |
| MAM33 | 2 | 0.6 | 2 | 0.8 |
| PFK26 | 2.5 | 0.5 | 2 | 0.9 |
| PET117 | 2.6 | 0.7 | 2 | 0.5 |
| ARN1 | 2 | 1 | 3 | 0.2 |
| TIS11 | 2.1 | 1.2 | 3.4 | 0.3 |
| HSP26 | 2.3 | 1 | 10.1 | 0.4 |
| TAF1 | 2.2 | 1 | 3.8 | 0.2 |
| FIT1 | 1.8 | 1 | 8.1 | 0.1 |
| FIT2 | 2 | 1.1 | 10.2 | 0.2 |
| Experiment | rho0
vs D pdr1 rho0 |
rho+
vs delta-pdr3 rho+ |
rho+ Pdr3-7
vs rho+ delta-pdr3 deltapdr1 |
| Strain | FY | FY | FY |
| PDR5 | 0.8 | 1 | 32 |
| PDR15 | 1.1 | 1 | 11.6 |
| YOR049c | 0.7 | 0.8 | 2.1 |
| YAL061w | 1.4 | 0.9 | 2.2 |
| YOR152c | ND | ND | 1.8 |
| PDR10 | ND | ND | 5 |
| SNQ2 | 1 | ND | 4 |
| PDR3 | 1 | ND | 7 |
| YKL071w | 0.9 | 0.8 | 1.2 |
| YGR035c | 0.6 | 0.8 | 1.3 |
| ICT1 | 0.4 | 0.9 | 1.4 |
| YLR346c | 0.6 | ND | 0.6 |