Welcome to the Bessereau Lab


What we work on

Chemical synapses are specialized intercellular junctions that allow fast and specific transmission between excitable cells and connect individual neurons into functional networks. Using the nematode Caenorhabditis elegans as a model system, we are investigating the mechanisms that govern the formation and the regulation of chemical synapses with a specific interest in nicotinic neurotransmission. The nematode C. elegans is a 1mm long non-parasitic soil worm which has a very simple nervous system : it only contains 302 neurons and about 7,000 chemical synapses. However, C. elegans expresses a wide-range of nicotinic acetylcholine receptors (nAChRs). In mammals, nicotinic acetylcholine receptors are involved in diverse physiological and pathological functions. Specifically, nAChRs represent the primary target of nicotine, the addictive component of tobacco smoke. Using the powerful genetic tools that are available in C. elegans, we are analyzing the molecular and cellular mechanisms that regulate nAChR distribution and function. Because of the evolutionary conservation between C. elegans and H. sapiens, the genes or pathways that regulate nicotinic neurotransmission in the nematode should yield the identification of novel genes or mechanisms that regulate nAChR function in humans.

Past events

Meeting Announcement

C. elegans : Development and Gene Expression Conference
This meeting will take place at EMBL Heidelberg, Germany in the Advanced Training Centre from 17-20 June 2010.
This topic meeting on C. elegans Development and Gene Expression will focus on the following areas :

Germline, meiosis & sex determination
Cell polarity and cell division
Cytoskeleton, Morphogenesis, Organelles
Signalling and post-embryonic development
Genomics and Transcription
Post-transcriptional and RNA-mediated regulation

If you are interested in participating please check the conference website and contact the conference organiser Bettina Schaefer - schaefer@embl.de :
www.embl.de/events/2010/ECE10


VER MIDI X - January 12, 2007

Program available for download click here.

Every year in January, French worm groups have a one day meeting called Ver Midi. The goal of this meeting is to get French C. elegans researchers together to discuss recent technological developments and especially to give a chance to young students and researchers to present their work. This meeting is open to anyone interested in attending.

We are pleased to announce that the VER MIDI X meeting will be held on January 12, 2007 at the Ecole Normale Supérieure in Paris . VER MIDI X will be hosted by the Bessereau lab and co-organized with Bernard Lakowski.

Talks can be given in French or English, but we encourage people to have slides and posters in English to facilitate communication with non French speakers. Anyone interested in attending the meeting should contact Valérie Robert. Deadline to submit a presentation is was December 8, 2006. No registration fee nor abstract is required.

Valérie Robert, Jean-Louis Bessereau, Bernard Lakowski .


VER MIDI IX - January 13, 2006

Program available for download : click here.

Every year in January, French worm groups have a one day meeting called Ver Midi. The goal of this meeting is to get French C. elegans researchers together to discuss recent technological developments and especially to give a chance to young students and researchers to present their work. This meeting is open to anyone interested in attending.

We are pleased to announce that the VER MIDI IX meeting will be held on January 13, 2006 at the Ecole Normale Supérieure in Paris . VER MIDI IX will be hosted by the Bessereau lab and co-organized with Bernard Lakowski.

Talks can be given in French or English, but we encourage people to have slides and posters in English to facilitate communication with non French speakers. Anyone interested in attending the meeting should contact Valérie Robert . Deadline to submit a presentation is December 12, 2005. No registration fee nor abstract is required.

Valérie Robert, Jean-Louis Bessereau, Bernard Lakowski .

Last update : 2011-03-31 15:17:30